The significance of sentinel lymph node micrometastasis in breast cancer: Comparing outcomes with and without axillary clearance.
Identifieur interne : 000992 ( Main/Exploration ); précédent : 000991; suivant : 000993The significance of sentinel lymph node micrometastasis in breast cancer: Comparing outcomes with and without axillary clearance.
Auteurs : Mina M G. Youssef [Royaume-Uni] ; Diane Cameron [Royaume-Uni] ; Philip H. Pucher [Royaume-Uni] ; Sisse Olsen [Royaume-Uni] ; Douglas Ferguson [Royaume-Uni]Source :
- Breast (Edinburgh, Scotland) [ 1532-3080 ] ; 2016.
Descripteurs français
- KwdFr :
- Aisselle, Carcinome canalaire du sein (), Carcinome canalaire du sein (anatomopathologie), Carcinome lobulaire (), Carcinome lobulaire (anatomopathologie), Complications postopératoires (épidémiologie), Estimation de Kaplan-Meier, Femelle, Humains, Lymphadénectomie (), Lymphoedème (épidémiologie), Mastectomie, Micrométastase tumorale (anatomopathologie), Métastase lymphatique, Noeud lymphatique sentinelle (anatomopathologie), Noeuds lymphatiques (anatomopathologie), Pronostic, Radiothérapie adjuvante, Récidive tumorale locale (épidémiologie), Survie sans rechute, Traitement médicamenteux adjuvant, Tumeurs du sein (), Tumeurs du sein (anatomopathologie), Études cas-témoins, Études rétrospectives.
- MESH :
- anatomopathologie : Carcinome canalaire du sein, Carcinome lobulaire, Micrométastase tumorale, Noeud lymphatique sentinelle, Noeuds lymphatiques, Tumeurs du sein.
- épidémiologie : Complications postopératoires, Lymphoedème, Récidive tumorale locale.
- Aisselle, Carcinome canalaire du sein, Carcinome lobulaire, Estimation de Kaplan-Meier, Femelle, Humains, Lymphadénectomie, Mastectomie, Métastase lymphatique, Pronostic, Radiothérapie adjuvante, Survie sans rechute, Traitement médicamenteux adjuvant, Tumeurs du sein, Études cas-témoins, Études rétrospectives.
English descriptors
- KwdEn :
- Axilla, Breast Neoplasms (pathology), Breast Neoplasms (therapy), Carcinoma, Ductal, Breast (pathology), Carcinoma, Ductal, Breast (therapy), Carcinoma, Lobular (pathology), Carcinoma, Lobular (therapy), Case-Control Studies, Chemotherapy, Adjuvant, Disease-Free Survival, Female, Humans, Kaplan-Meier Estimate, Lymph Node Excision (methods), Lymph Nodes (pathology), Lymphatic Metastasis, Lymphedema (epidemiology), Mastectomy, Neoplasm Micrometastasis (pathology), Neoplasm Recurrence, Local (epidemiology), Postoperative Complications (epidemiology), Prognosis, Radiotherapy, Adjuvant, Retrospective Studies, Sentinel Lymph Node (pathology).
- MESH :
- epidemiology : Lymphedema, Neoplasm Recurrence, Local, Postoperative Complications.
- methods : Lymph Node Excision.
- pathology : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Lobular, Lymph Nodes, Neoplasm Micrometastasis, Sentinel Lymph Node.
- therapy : Breast Neoplasms, Carcinoma, Ductal, Breast, Carcinoma, Lobular.
- Axilla, Case-Control Studies, Chemotherapy, Adjuvant, Disease-Free Survival, Female, Humans, Kaplan-Meier Estimate, Lymphatic Metastasis, Mastectomy, Prognosis, Radiotherapy, Adjuvant, Retrospective Studies.
Abstract
Management of micrometastasis in the sentinel node is a controversial topic. Most of the guidelines don't recommend further axillary treatment if micrometastasis are the only finding in the sentinel node. However, some evidence suggests that micrometastasis have significant effect on long term outcomes and therefore indicate systemic treatment.
DOI: 10.1016/j.breast.2016.09.005
PubMed: 27668857
Affiliations:
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Youssef</name><affiliation wicri:level="1"><nlm:affiliation>Department of Breast Surgery, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK. 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uniqKey="Ferguson D" first="Douglas" last="Ferguson">Douglas Ferguson</name><affiliation wicri:level="1"><nlm:affiliation>Department of Breast Surgery, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Breast Surgery, Royal Devon and Exeter NHS Foundation Trust, Exeter</wicri:regionArea><wicri:noRegion>Exeter</wicri:noRegion></affiliation></author></analytic><series><title level="j">Breast (Edinburgh, Scotland)</title><idno type="eISSN">1532-3080</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Axilla</term><term>Breast Neoplasms (pathology)</term><term>Breast Neoplasms (therapy)</term><term>Carcinoma, Ductal, Breast (pathology)</term><term>Carcinoma, Ductal, Breast (therapy)</term><term>Carcinoma, Lobular (pathology)</term><term>Carcinoma, Lobular (therapy)</term><term>Case-Control Studies</term><term>Chemotherapy, Adjuvant</term><term>Disease-Free Survival</term><term>Female</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Lymph Node Excision (methods)</term><term>Lymph Nodes (pathology)</term><term>Lymphatic Metastasis</term><term>Lymphedema (epidemiology)</term><term>Mastectomy</term><term>Neoplasm Micrometastasis (pathology)</term><term>Neoplasm Recurrence, Local (epidemiology)</term><term>Postoperative Complications (epidemiology)</term><term>Prognosis</term><term>Radiotherapy, Adjuvant</term><term>Retrospective Studies</term><term>Sentinel Lymph Node (pathology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Aisselle</term><term>Carcinome canalaire du sein ()</term><term>Carcinome canalaire du sein (anatomopathologie)</term><term>Carcinome lobulaire ()</term><term>Carcinome lobulaire (anatomopathologie)</term><term>Complications postopératoires (épidémiologie)</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Humains</term><term>Lymphadénectomie ()</term><term>Lymphoedème (épidémiologie)</term><term>Mastectomie</term><term>Micrométastase tumorale (anatomopathologie)</term><term>Métastase lymphatique</term><term>Noeud lymphatique sentinelle (anatomopathologie)</term><term>Noeuds lymphatiques (anatomopathologie)</term><term>Pronostic</term><term>Radiothérapie adjuvante</term><term>Récidive tumorale locale (épidémiologie)</term><term>Survie sans rechute</term><term>Traitement médicamenteux adjuvant</term><term>Tumeurs du sein ()</term><term>Tumeurs du sein (anatomopathologie)</term><term>Études cas-témoins</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Carcinome canalaire du sein</term><term>Carcinome lobulaire</term><term>Micrométastase tumorale</term><term>Noeud lymphatique sentinelle</term><term>Noeuds lymphatiques</term><term>Tumeurs du sein</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Lymphedema</term><term>Neoplasm Recurrence, Local</term><term>Postoperative Complications</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Lymph Node Excision</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Breast Neoplasms</term><term>Carcinoma, Ductal, Breast</term><term>Carcinoma, Lobular</term><term>Lymph Nodes</term><term>Neoplasm Micrometastasis</term><term>Sentinel Lymph Node</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Breast Neoplasms</term><term>Carcinoma, Ductal, Breast</term><term>Carcinoma, Lobular</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Complications postopératoires</term><term>Lymphoedème</term><term>Récidive tumorale locale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Axilla</term><term>Case-Control Studies</term><term>Chemotherapy, Adjuvant</term><term>Disease-Free Survival</term><term>Female</term><term>Humans</term><term>Kaplan-Meier Estimate</term><term>Lymphatic Metastasis</term><term>Mastectomy</term><term>Prognosis</term><term>Radiotherapy, Adjuvant</term><term>Retrospective Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Aisselle</term><term>Carcinome canalaire du sein</term><term>Carcinome lobulaire</term><term>Estimation de Kaplan-Meier</term><term>Femelle</term><term>Humains</term><term>Lymphadénectomie</term><term>Mastectomie</term><term>Métastase lymphatique</term><term>Pronostic</term><term>Radiothérapie adjuvante</term><term>Survie sans rechute</term><term>Traitement médicamenteux adjuvant</term><term>Tumeurs du sein</term><term>Études cas-témoins</term><term>Études rétrospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Management of micrometastasis in the sentinel node is a controversial topic. Most of the guidelines don't recommend further axillary treatment if micrometastasis are the only finding in the sentinel node. However, some evidence suggests that micrometastasis have significant effect on long term outcomes and therefore indicate systemic treatment.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Londres</li></region><settlement><li>Londres</li></settlement></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Youssef, Mina M G" sort="Youssef, Mina M G" uniqKey="Youssef M" first="Mina M G" last="Youssef">Mina M G. Youssef</name></noRegion><name sortKey="Cameron, Diane" sort="Cameron, Diane" uniqKey="Cameron D" first="Diane" last="Cameron">Diane Cameron</name><name sortKey="Ferguson, Douglas" sort="Ferguson, Douglas" uniqKey="Ferguson D" first="Douglas" last="Ferguson">Douglas Ferguson</name><name sortKey="Olsen, Sisse" sort="Olsen, Sisse" uniqKey="Olsen S" first="Sisse" last="Olsen">Sisse Olsen</name><name sortKey="Pucher, Philip H" sort="Pucher, Philip H" uniqKey="Pucher P" first="Philip H" last="Pucher">Philip H. Pucher</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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